AugaOne™
AugaOne™ is the first plug-and-play, in-line sensor system for real-time detection and measurement of specific proteins during chromatography purification in process development. Powered by proprietary Localized Surface Plasmon Resonance (LSPR) technology, it delivers label-free, high-sensitivity measurements directly in the flow without the need for sample pretreatment.
Designed for downstream bioprocess development, AugaOne™ provides automated, specific in-line data with minimal setup. It integrates seamlessly with existing chromatography systems, reduces lead times, and enables actionable insights from day one.
AugaOne™
AugaOne™ is the first plug-and-play, in-line sensor system for real-time detection and measurement of specific proteins during chromatography purification in process development. Powered by proprietary Localized Surface Plasmon Resonance (LSPR) technology, it delivers label-free, high-sensitivity measurements directly in the flow without the need for sample pretreatment.
Designed for downstream bioprocess development, AugaOne™ provides automated, specific in-line data with minimal setup. It integrates seamlessly with existing chromatography systems, reduces lead times, and enables actionable insights from day one.
AugaOne™
AugaOne™ is the first plug-and-play, in-line sensor system for real-time detection and measurement of specific proteins during chromatography purification in process development. Powered by proprietary Localized Surface Plasmon Resonance (LSPR) technology, it delivers label-free, high-sensitivity measurements directly in the flow without the need for sample pretreatment.
Designed for downstream bioprocess development, AugaOne™ provides automated, specific in-line data with minimal setup. It integrates seamlessly with existing chromatography systems, reduces lead times, and enables actionable insights from day one.
Replace time-consuming off-line analyses with in-line analytics, thereby eliminating the need for sample treatment procedures.
Selective detection of IgG within complex sample matrices using specific ligands.
Sensor signals are captured at one-second intervals, enabling real-time analytical measurements.
With its add-on capability, and quick, straightforward installation, the system offers a minimal entry barrier and can be used from day one.
Unique stability in providing reliable and reproducible measurements under changing bioprocess conditions. Delivers immediate resource savings, including over 20% less affinity resin usage, reduced buffer and energy consumption, and a smaller environmental footprint.
Replace time-consuming off-line analyses with in-line analytics, thereby eliminating the need for sample treatment procedures.
Selective detection of IgG within complex sample matrices using specific ligands.
Sensor signals are captured at one-second intervals, enabling real-time analytical measurements.
With its add-on capability, and quick, straightforward installation, the system offers a minimal entry barrier and can be used from day one.
Unique stability in providing reliable and reproducible measurements under changing bioprocess conditions. Delivers immediate resource savings, including over 20% less affinity resin usage, reduced buffer and energy consumption, and a smaller environmental footprint.
Built on proprietary LSPR-based fiber optic detection, AugaOne™ utilizes single-use, ligand-functionalized sensor chips to achieve sub-μg/mL sensitivity in complex downstream matrices. The system integrates seamlessly with existing chromatography setups and supports real-time Process Analytical Technology (PAT) implementation through OPC-compatible software.
The hardware consists of a compact optical unit with integrated LED and CMOS detector, stainless-steel flow cells (0.01–250 mL/min), and robust sensor chips functionalized with Protein A, G, or L. The chips provide specific, reproducible binding with minimal signal variation and allow for multi-cycle use through on-chip regeneration within a single process run.
The dedicated software enables automated signal acquisition for real-time monitoring with a sampling interval of about 1 second. Through OPC DA/UA integration, it efficiently collects and displays data from ÄKTA purification system detectors, such as UV absorbance, conductivity, and pH, alongside data from our sensor for a complete process overview.
Certified with CE-marking and validated in GMP-like environments, AugaOne™ reduces lead times, manual work, and analytical overhead making it a critical enabler for modern downstream process development.
Sensor Chips
Flow Cell
Optical Unit
Optical Unit
Dimensions:
Weight:
Light source:
Minimum light source lifetime:
Detector:
Temperature range:
Power supply:
Data transfer:
W205 x D177 x H66 mm
1.5 kg
Warm white LED 3000 K
10 000 h
CMOS
10–30 °C
5 V DC @ 700 mA
USB3
Flow Cell
Dimensions:
Weight:
Material:
Design:
Flow rate:
Dead volume FC34 / FC15:
W50 x D24 x H71 mm
304 g
Medical grade stainless steel
Single channel
0.01-250 mL/min
213 µL / 82 µL
Application Notes
Brochures & Data Sheets
Presentations
Scientific Publications
Built on proprietary LSPR-based fiber optic detection, AugaOne™ utilizes single-use, ligand-functionalized sensor chips to achieve sub-μg/mL sensitivity in complex downstream matrices. The system integrates seamlessly with existing chromatography setups and supports real-time Process Analytical Technology (PAT) implementation through OPC-compatible software.
The hardware consists of a compact optical unit with integrated LED and CMOS detector, stainless-steel flow cells (0.01–250 mL/min), and robust sensor chips functionalized with Protein A, G, or L. The chips provide specific, reproducible binding with minimal signal variation and allow for multi-cycle use through on-chip regeneration within a single process run.
The dedicated software enables automated signal acquisition for real-time monitoring with a sampling interval of about 1 second. Through OPC DA/UA integration, it efficiently collects and displays data from ÄKTA purification system detectors, such as UV absorbance, conductivity, and pH, alongside data from our sensor for a complete process overview.
Certified with CE-marking and validated in GMP-like environments, AugaOne™ reduces lead times, manual work, and analytical overhead making it a critical enabler for modern downstream process development.
Sensor Chips
Flow Cell
Optical Unit
Optical Unit:
Dimensions:
Weight:
Light source:
Min. light source lifetime:
Detector:
Temperature range:
Power supply:
Data transfer:
W205 x D177 x H66 mm
1.5 kg
Warm white LED 3000 K
10 000 h
CMOS
10–30 °C
5 V DC @ 700 mA
USB3
Flow Cell:
Dimensions:
Weight:
Material:
Design:
Flow rate:
Dead vol. FC34/FC15:
W50 x D24 x H71 mm
304 g
Medical grade stainless steel
Single channel
0.01-250 mL/min
213 µL / 82 µL
Application Notes
Brochures and Data Sheets
Presentations
Scientific Publications
Webinars
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